Page 22 - MEH_Supplement_Nov-Dec_2012

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patients do not respond to drug therapy –
the first line of treatment for the disease –
surgical removal of part or nearly all of the
pancreas (pancreatectomy) is needed.
CHOP has treated more than 400 HI
patients and performed more than 300
pancreatectomies – a level of expertise
unmatched anywhere in the world. There are
two forms of HI: diffuse (all beta cells in the
pancreas are affected) and focal (only a small
area of the pancreas is affected). CHOP’s
team uses advanced positron emission
tomography (PET) scanning to diagnose
diffuse or focal disease and, in the latter case,
to determine precise locations of focal
lesions. Under a Food and Drug
Administration-approved protocol, the
DOPA PET scan, which CHOP surgeons
have called “the GPS of imaging,” has helped
CHOP achieve a cure rate of 95 percent for
focal HI. The team is also at the forefront of
developing innovative treatments for HI that
could offer new hope to patients, especially
those with diffuse HI, many of whom
continue to have hypoglycemia after surgery.
Pediatric Thyroid Center
The Pediatric Thyroid Center, led by
Andrew J. Bauer, M.D., is a multidiscipli-
nary center that cares for children and
adolescents with thyroid conditions,
including difficult-to-treat patients with
unusual forms of hypothyroidism and
hyperthyroidism. The center also offers
specialized expertise on the evaluation and
care of patients with thyroid nodules and
thyroid cancer. The members of the
center’s experienced, multidiscipli-
nary team work together to
ensure seamless, coordi-
nated care for each
patient, from
evaluation to surgical intervention to
radioactive iodine therapy. Each year, the
team evaluates more than 120 new patients
with thyroid nodules, performs more than
60 thyroid surgeries, and expertly manages
more than 100 thyroid cancer patients.
The CHOP team is actively involved in
developing specific practice procedures for
pediatric thyroid cancer patients, who have
different responses to therapy compared to
adults. One example is the use of single
photon emission computed tomography
(SPECT) with intraoperative radioguided
surgery, an innovative technique designed
to optimize surgery while reducing the risk
of complications. CHOP’s center is the
busiest pediatric thyroid center in the
United States, and the team’s sensitivity to
the unique needs of young thyroid disease
patients sets it apart from other hospitals,
where pediatric patients are often treated
on the same protocols as adults.
Collaborative Care from Top Specialists
The Children’s Hospital of Philadelphia is
recognized around the world for providing
excellent care for both rare and common
conditions. In
U.S. News & World Report
2012-13 survey of Best Children’s
Hospitals, CHOP earned No. 1 rankings in
more specialties than any other children’s
hospital in the nation and tied for the No.
1 overall ranking on the
U.S. News
Roll. Our top specialists work together on
multidisciplinary teams to provide the best
care for every child.
International Patient Services
Our International Patient Services team
works with families before, during and after
their visit to The Children’s Hospital of
Philadelphia, assisting with travel and
lodging, arranging for medical interpreters,
scheduling appointments and more.
To learn more about International Patient
Services at The Children’s Hospital of
Philadelphia, please call 001-267-426-6298
or visit
As one of the largest centers of its kind in
the United States, the Division of Diabetes
and Endocrinology at The Children’s
Hospital of Philadelphia treats children
from all over the world, providing compre-
hensive, multidisciplinary care. The divi-
sion, which is led by Michael A. Levine,
M.D., provides consultation in a wide
variety of endocrine and metabolic disor-
ders in Centers of Excellence, including the
Diagnostic and Research Growth Center,
which cares for children with growth and
pubertal disorders; the Diabetes Center for
Children, which cares for more than 2,000
children with both Type 1 and Type 2
diabetes; and the Center for Bone Health,
which cares for children who have or are at
risk for weak bones and rickets.
The division also has centers for congen-
ital hyperinsulinism and thyroid disorders,
conditions that require a level of expertise
that only CHOP can provide.
Congenital Hyperinsulinism Center
Developed by Charles Stanley, M.D., and
now led by Diva D. De León, M.D.,
CHOP’s Congenital Hyperinsulinism
Center is the only program of its kind in the
United States, uniting the skills of pediatric
endocrinologists, surgeons, pathologists,
neonatologists, anesthesiologists, radiolo-
gists, nurses and researchers to treat and
cure children with congenital hyperin-
sulinism (HI), a rare disease that causes
severe, persistent
expert, highly
care. If
Innovative treatments, specialized
care for endocrine disorders
| M I D D L E E A S T H E A L T H
The Children’s Hospital of Philadelphia
An update from the children’s hospital ranked No. 1 in the
United States in diabetes and endocrinology